Abstract Accessories Background Currently available anti-leukemia drugs have shown limited success in the treatment of acute myeloid leukemia (AML) due to their poor access to bone marrow niche supporting leukemic cell proliferation.Results Herein, we report a bone marrow-targetable green tea catechin-based micellar nanocomplex for synergistic AML
Glioblastoma (GBM), a highly malignant glioma of the central nervous system, is the most dread and BLADDER ONE FOR WOMEN common brain tumor with a high rate of therapeutic resistance and recurrence.Currently, the clinical treatment methods are surgery, radiotherapy, and chemotherapy.However, owning to the highly invasive nature of GBM, it is diffic
Automobile body design is performed using structural analysis by numerical calculation, but to make it efficient, it is important to establish a technique that can quickly derive the structure satisfying the target value.Although optimization methods are used in many design studies, problems sometimes arise in the actual design stage, and conventio
Underwater gliders are unmanned undersea vehicles that utilize hydrodynamic principles to glide through water.They rely on a range of technologies, including overall design principles such as hydrodynamic shape and pressure-resistant hull, specific unit technologies such as buoyancy-driven propulsion, attitude adjustment, energy management, intelli